AN IMPROVED PROCESS FOR THE CONVERSION OF 2-(METHYLTHIO)-5-(TRIFLUOROMETHYL)-1,3,4-THIADIAZOLE (TDA) TO 2-(METHYLSULFONYL)-5-(TRIFLUOROMETHYL)-1,3,4-THIADIAZOLE (TDA SULFONE)

摘要

The present invention provides a process for making thiadiazolesulfones. In particular, the present process is used to make2--(methylsulfonyl)-5-(trifluoromethyl)-1,3,4-thiadiazole using catalyticoxidation in the presence of a suitable oxidizing agent. The catalystsystem used for the oxidation reaction is a mixture of glacial acetic acidand a tungsten catalyst. The tungsten catalyst is preferably selected fromthe group consisting of sodium tungstate, potassium tunstate, and tungsticacid.