首页> 外国专利> 2- (pyrazin-2-yl) -thiazole and 2- (1h-pyrazol-3-yl) -thiazole derivatives as well as related compounds as stearoyl-CoA desaturase (SCD) inhibitors for the treatment of metabolic, cardiovascular and other disorders

2- (pyrazin-2-yl) -thiazole and 2- (1h-pyrazol-3-yl) -thiazole derivatives as well as related compounds as stearoyl-CoA desaturase (SCD) inhibitors for the treatment of metabolic, cardiovascular and other disorders

机译:2-(吡嗪-2-基)-噻唑和2-(1h-吡唑-3-基)-噻唑衍生物以及相关化合物,如硬脂酰CoA去饱和酶(SCD)抑制剂,用于治疗代谢,心血管疾病和其他疾病

摘要

The present invention provides heterocyclic derivatives of formula I that modulate the activity of stearoyl-CoA desaturase. Methods of using such derivatives to modulate the activity of stearoyl-CoA desaturase and pharmaceutical compositions comprising such derivatives are also encompassed. wherein Q is
机译:本发明提供了调节硬脂酰辅酶A去饱和酶活性的式I杂环衍生物。还涵盖了使用此类衍生物调节硬脂酰辅酶A去饱和酶活性的方法,以及包含此类衍生物的药物组合物。其中Q是

著录项

  • 公开/公告号AU2007288245A1

    专利类型

  • 公开/公告日2008-02-28

    原文格式PDF

  • 申请/专利权人 NOVARTIS AG;XENON PHARMACEUTICALS INC.;

    申请/专利号AU20070288245

  • 发明设计人 ZAIHUI ZHANG;NATALIE DALES;

    申请日2007-08-22

  • 分类号A61K31/427;A61K31/497;A61P3/04;A61P3/06;A61P3/10;A61P9;A61P9/12;A61P17;A61P17/06;A61P17/10;C07D417/04;C07D417/14;

  • 国家 AU

  • 入库时间 2022-08-21 20:02:46

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