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《中国化学快报:英文版》
>Synthesis of C-Nucleoside Analogues: 2-2-(Hydroxymethyl)-1,3-dioxolan-5-yl1,3-thiazole-4-carboxamide and 2-2-(Mercaptometh-yl)-1,3-dioxolan-5-yl 1,3-thiazole-4-carboxamide
Synthesis of C-Nucleoside Analogues: 2-2-(Hydroxymethyl)-1,3-dioxolan-5-yl1,3-thiazole-4-carboxamide and 2-2-(Mercaptometh-yl)-1,3-dioxolan-5-yl 1,3-thiazole-4-carboxamide
Novel C-nucleosides of tiazofurin analogue (2-[2-(hydroxymethyl)-1, 3-dioxolan-5-yl]1, 3-thiazole-4-carboxamide) and its thiol-substituted derivative (2-[2-(mercaptomethyl)-1,3-dioxolan -5-yl]1, 3-thiazole-4-carboxamide) were synthesized from methyl acrylate through a multistep procedure. Their structures were confirmed by IR, 1HNMR, 13CNMR and elemental analysis.
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