METHODS FOR PROMOTING COUPLING BETWEEN BONE FORMATION AND RESORPTION

摘要

Methods and compositions for promoting coupling between bone formation and bone resorption are provided. The method related to administering a therapeutically effective amount of a rho inhibitor, a Transforming Growth Factor ß receptor I (TßRI) inhibitor or a combination thereof to a subject. The methods and compositions are useful, for example, in a subject with a disorder linked to an imbalance between bone formation and bone resorption.