首页> 外国专利> USING NONHUMAN ANIMAL MODEL, METHOD OF MEASURING TRANSCRIPTION ACTIVITY, METHOD OF MEASURING CELL QUANTITY AND METHOD OF MEASURING TUMOR VOLUME

USING NONHUMAN ANIMAL MODEL, METHOD OF MEASURING TRANSCRIPTION ACTIVITY, METHOD OF MEASURING CELL QUANTITY AND METHOD OF MEASURING TUMOR VOLUME

机译:使用非人类动物模型,转录活性的测定方法,细胞量的测定方法和肿瘤体积的测定方法

摘要

In a nonhuman animal model that produces a secretory protein, which is obtained by transplanting secretory protein-expression vector-transfected cells into a nonhuman animal, an amount of the secretory protein is measured and, based on the amount of the secretory protein, transcriptional activity, number of the transplanted cells, and tumor volume is measured. Further, screening of a compound that affects a transcriptional activity, number of transplanted cells, or tumor volume is performed by using the nonhuman animal model to which a compound has been administered.
机译:在产生分泌蛋白的非人类动物模型中,该模型是通过将分泌表达蛋白的载体转染的细胞移植到非人类动物中而获得的,测量该分泌蛋白的量,并基于该分泌蛋白的量来转录活性,移植细胞的数量和肿瘤体积。此外,通过使用已经施用了化合物的非人类动物模型来进行对影响转录活性,移植细胞数量或肿瘤体积的化合物的筛选。

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