O-DESULFATED HEPARINS TREATING ACUTE EXACERBATIONS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

摘要

The present invention provides methods for treating and preventing acute exacerbations of Chronic Obstructive Pulmonary Disease. The methods particularly comprise administering to a patient have COPD a composition comprising O- desulfated heparin. The administration can be after onset of one or more symptoms indicating an exacerbation of COPD or prior to onset of such symptoms. After onset of an acute exacerbation, administration of the O-desulfated heparin is particularly beneficial for reducing the time of hospitalization of the patient and for reducing lung inflammation.