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FOUR-DIMENSIONAL IMAGING OF PERIODICALLY MOVING OBJECTS VIA POST-ACQUISITION SYNCHRONIZATION OF NONGATED SLICE-SEQUENCES
FOUR-DIMENSIONAL IMAGING OF PERIODICALLY MOVING OBJECTS VIA POST-ACQUISITION SYNCHRONIZATION OF NONGATED SLICE-SEQUENCES
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机译:通过非门限切片序列的采集后同步对周期性运动的物体进行四维成像
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摘要
When 'the studied motion is periodic, such as Or a beating heat, Q is possible to acquire successive sets of two dimensional plus time data slice-sequences at increasing depths over at.least one time period which are later rearranged to recover a three dimensional time sequence. Since gating signals are either unavailable or cumbersome to acquire in microscopic organisms, the invention is a method for reconstructing volumes based solely on the information contained in the image sequences. The central part of the algorithm is a least-squares minimization of an objective criterion that depends on the similarity between the data from neighboring depths. Owing to a wavelet-based multiresolution approach, the method is robust to common con-focal microscopy artifacts. The method is validated on both simulated data and in-vivo measurements.
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