首页>
外国专利>
MUSCARINIC RECEPTOR ANTAGONISTS OR AGENTS FOR THE PREVENTION AND TREATMENT OF NERVOUS SYSTEM DISEASES BY ORGANOPHOSPHATE INTOXICATION CONTAINING 2-PHENYL-2-CARBOXYLIC ACID ESTER DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AS AN ACTIVE INGREDIENT
MUSCARINIC RECEPTOR ANTAGONISTS OR AGENTS FOR THE PREVENTION AND TREATMENT OF NERVOUS SYSTEM DISEASES BY ORGANOPHOSPHATE INTOXICATION CONTAINING 2-PHENYL-2-CARBOXYLIC ACID ESTER DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AS AN ACTIVE INGREDIENT
Muscarinic receptor antagonists or agents are provided to struggle with the muscarinic receptor, prevent and treat nervous system diseases such as convulsion, Parkinson's disease and epilepsy, and detoxify the poisoning of nerve agents or organophosphate fertilizer. The muscarinic receptor antagonists or agents contain 2-phenyl-2-carboxylic acid derivatives represented by the formula(1) or pharmaceutically acceptable salts thereof as effective ingredients, wherein X is hydrogen, halogen, amino, nitro, C1-C5 linear or branched chain alkyl or C1-C5 alkoxy and is positioned in an ortho-, metha- or para-site; Y is C1-C7 linear or branched chain alkyl; R1 and R2 are each independently C1-C7 linear or branched chain alkyl and form a ring together; and n is an integer from 1 to 4.
展开▼