PROCESS FOR PRODUCING VALERIANA FAURIEI ROOTS, VALERIANA FAURIEI ROOTS PRODUCED BY THE PROCESS, AND PROCESS FOR PRODUCING VALERENIC ACIDS AND VALEPOTRIATES FROM THE ROOTS

摘要

A method for producing Valeriana fauriei roots is provided to mass-produce the Valeriana fauriei roots economically in a bio-reactor, which contains high contents of valerenic acids and valepotriates comparable to those of open-field cultured Valeriana fauriei roots. A culture medium for culturing Valeriana fauriei roots in a bio-reactor comprises 7% of sucrose in a B5 medium and has a pH of 5.5-6.0. A method for producing the Valeriana fauriei roots comprises a step of culturing the Valeriana fauriei roots in the bio-reactor including the culture medium at a temperature of 15-25 deg.C with an air injection amount of 0.2-0.5 vvm for 4-6 weeks. A method for producing valerenic acids and valepotriates comprises the steps of: (a) culturing the Valeriana fauriei roots in the bio-reactor including the culture medium; and (b) extracting the valerenic acid and valepotriates from the cultured Valeriana fauriei roots. Further, a concentration rate of KNO:(NH4)2SO4 is 24~25:1.0 in the B5 medium.