FIELD: organic chemistry, chemical technology.;SUBSTANCE: invention relates to chemistry of triterpenoid esters of lupane group, namely, to a method for synthesis of novel compounds representing 3β,28-di-O,O'-aroylacetate- and 3β,28-di-O,O'-aroylpyruvates of betulin of the formula (I): wherein Ar means C6H5, p-CH3C6H4, p-C2H5O-C6H4; n = 0, 1 possessing analgesic activity. Method involves interaction of 5-aryl-2,3-dihydrofuran-2,3-diones with betulin at heating in toluene medium at temperature 60-70°C for 5-6 h, or at boiling in toluene for 25-30 min, respectively. Invention provides a simple synthesis of novel active compounds from available raw as potential drugs that is not described in special literature.;EFFECT: improved method of synthesis.;3 cl, 1 tbl, 7 ex
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机译：化合物的合成方法技术领域本发明涉及环戊烷基三萜酯的化学，即涉及代表3β，28-di-O，O′-芳酰基乙酸酯和3β的新型化合物的合成方法。式（I）的桦木酚的28，di-O，O'-芳酰基丙酮酸酯：，其中Ar表示C 6 H 5 ，p-CH 3 C 6 H < Sub> 4 ，pC 2 H 5 OC 6 H 4 ; n = 0，1具有镇痛作用。该方法涉及5-芳基-2,3-二氢呋喃-2,3-二酮与白藜芦醇在甲苯介质中于60-70℃的温度下加热5-6小时，或在甲苯中沸腾25-30分钟，与白蛋白相互作用，分别。本发明提供了从潜在的潜在原料药中合成新型活性化合物的简单方法，该方法未在特殊文献中进行描述。效果：改进的合成方法; 3 cl，1 tbl，7 ex
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