METHOD OF SYNTHESIS OF 3amp;prime;, 4amp;prime;, -³H - 16amp;alpha;, 17amp;alpha;-CYCLOHEXANOPREGN-4-EN-3, 20-DIONE LABELED WITH TRITIUM

摘要

FIELD: organic chemistry. SUBSTANCE: synthesis is carried out by reaction of corresponding steroid and ethylene glycol following by treatment with gaseous tritium in the presence of Pd-catalyst in organic solvent and splitting off of ethylene glycol protected group in acid medium. Yield of the end products is 67% , molar activity is 1.97 PBq/mole, radiochemical purity is 95-97% . EFFECT: high molar activity of product. 1 tbl