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Vaccination against host cell-associated herpesvirus

机译:针对宿主细胞相关疱疹病毒的疫苗接种

摘要

The invention relates to the field of so-called host cell-associated herpesviruses such as Marek's disease like virus (MDV) of poultry and of Varicella Zoster Virus (VZV) of man and to vaccination against disease caused by these viruses. The invention provides a vaccine directed against an infection caused by an herpesvirus that is essentially host cell associated comprising a recombinant viral genome derived from said herpesvirus, said genome allowing recombination essentially free of said host cell.
机译:本发明涉及与宿主细胞相关的疱疹病毒,例如家禽的马立克氏病样病毒(MDV)和人的水痘带状疱疹病毒(VZV),并且涉及针对由这些病毒引起的疾病的疫苗接种。本发明提供了针对由疱疹病毒引起的感染的疫苗,所述疱疹病毒基本上是与宿主细胞相关的宿主细胞,其包含衍生自所述疱疹病毒的重组病毒基因组,所述基因组允许重组而基本上不含所述宿主细胞。

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