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Pseudomonas-derived PA-IL lectin, PA-IIL lectin or a glycomimetic inhibitor of both lectins

机译:假单胞菌来源的PA-IL凝集素,PA-IIL凝集素或两种凝集素的拟糖抑制剂

摘要

Compositions and methods are provided related to Pseudomonas bacteria. The compositions and methods may be used for diagnosis and therapy of medical conditions involving infection with Pseudomonas bacteria. Such infections include Pseudomonas aeruginosa in the lungs of patients with cystic fibrosis. A compound useful in the present methods may be used in combination with a therapeutic agent or may be linked to a therapeutic agent. Pseudomonas bacteria may be inhibited by blocking colonization, inhibiting virulence factors, arresting growth or killing the bacteria.
机译:提供了与假单胞菌细菌有关的组合物和方法。所述组合物和方法可用于诊断和治疗涉及假单胞菌细菌感染的医学病症。此类感染包括囊性纤维化患者肺部的铜绿假单胞菌。可用于本方法的化合物可与治疗剂组合使用或可与治疗剂连接。假单胞菌细菌可通过阻止定殖,抑制毒力因子,阻止细菌生长或杀死细菌来抑制。

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