Production method of L karunichin which uses the enteric bacteria course being attached microbe and the said microbe which possess the gene which participates in L karunichin biosynthesis

摘要

Provided is a microorganism that belongs to Enterobacteriacae and a method of producing L-carnitine using the same. The microorganism includes polynucleotide encoding activity of S-adenosylmethionine-6-N-iysine methyltransferase from Neurospora crassa, polynucleotide encoding activity of 6-N-trimethyllysine hydroxylase, polynucleotide encoding activity of 3-hydroxy-6-N-trimethyllysine aldolase, and polynucleotide encoding activity of -trimethylaminoaldehyde dehydrogenase and y-butyrobetaine hydroxylase.