The present invention comprises propofol 0.1-2 w / v%, oily component 10-20 w / v% and emulsifier 2-5 w / v%, and the blending ratio of oily component to propofol is in the range of about 5 to 200 times by weight The propofol-containing fat emulsion in which the blending ratio of the emulsifier to propofol is in the range of about 0.9 to 50 times by weight and the average particle diameter of the emulsified particles is 180 nm or less, and a method for producing the same. The propofol-containing fat emulsion of the present invention reduces vascular pain at the time of administration without blending a local anesthetic such as lidocaine.
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