(e)-n- mono alkyl -3- oxo -3- (2- chieniru) propene amine and its production method, and (E and Z) -N- mono alkyl -3- oxo -3- (2- chieniru) production method of propene amine

摘要

(E and Z) the -N- mono alkyl -3- oxo -3- (2- chieniru) the (e)-n- mono alkyl -3- oxo -3- which is used for method, and that production method of producing propene amine easily at high yield (2- chieniru) propene amine and its production method are offered. The general system which features that grain size divides the crystal of 100 millimicrons or less from the crystal which this invention made crystallize, precipitated, (Z) the -N- mono alkyl -3- oxo -3- (2- chieniru) keeping the solution which melts propene amine in the solvent, below the 25C, (1);[Conversion 1](In formula, R carbon count shows alkyl group 1 - 4.)So the (e)-n- mono alkyl -3- oxo -3- which is displayed (2- chieniru) production method of propene amine; And, - oxo -- (2- chieniru) reacting with the alkaline metal salt and the mono alkyl amine compound of propanal, adding the water insoluble organic solvent to the reaction liquid which can, the separate liquids doing and in the organic layer which can, the (e)-n- mono alkyl -3- oxo -3- (2- chieniru) adding the seed crystal which includes propene amine, it features that you keep below the 25C (E and Z) the -N- mono alkyl -3- oxo -3- (2- chieniru) production method of propene amine is offered.