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Analog compounds of analgesic peptides derived from the venom of crotalus durissus terrificus snakes, their uses, compositions, methods of preparation and purification

机译:蛇毒蛇毒的镇痛肽类似物化合物,其用途,组成,制备和纯化方法

摘要

The present invention refers to analog compounds of peptides having the amino acid sequences SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3 or SEQ ID NO: 4, including analgesic peptides derived from snakes of species such as Crotalus durissus terrificus; their uses in the treatment, diagnosis and prevention of painful conditions or mediated by opioid receptors, their pharmaceutical compositions and their methods of preparation and purification, including their uses in the identification of analgesic compounds.
机译:本发明涉及具有氨基酸序列SEQ ID NO:1,SEQ ID NO:2,SEQ ID NO:3或SEQ ID NO:4的肽的类似物化合物,包括衍生自诸如<I之类的蛇的止痛肽。 > Crotalus durissus terrificus; 它们在治疗,诊断和预防疼痛状况或由阿片受体介导的疼痛中的用途,其药物组合物及其制备和纯化方法,包括在鉴定镇痛化合物中的用途。

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