首页>
外国专利>
Recombinant method for the production of a monoclonal antibody to CD52 for the treatment of chronic lymphocytic leukemia
Recombinant method for the production of a monoclonal antibody to CD52 for the treatment of chronic lymphocytic leukemia
展开▼
机译:重组抗CD52单克隆抗体的生产方法,用于治疗慢性淋巴细胞性白血病
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention relates to the recombinant method used for the production of soluble form monoclonal antibody that binds to CD52. The procedure describes the de novo synthesis of the nucleic acid sequence encoding anti-CD 52, transformation of the constructed nucleic acid sequences into competent bacteria and the sub-cloning of the same into mammalian expression vectors for expression of the desired protein. DNA constructs comprising the control elements associated with the gene of interest has been disclosed. The nucleic acid sequence of interest has been codon optimized to permit expression in the suitable mammalian host cells.
展开▼