QUARTZ GLASS MICRO-PHOTOREACTOR AND SYNTHESIS OF 10-HYDROXYCAMPTOTHECIN AND 7-ALKYL 10-HYDROXYCAMPTOTHECIN

摘要

A process for the production of 10-hydroxycamptothecin;hydroxycamptothecin and/or of 7-alkyl 10-hydroxycamptothecin, with the steps ofA Providing a continuous fluid stream with a thickness d of a solution of camptothecin N-oxide or 7-alkyl camptothecin N-oxide; andB. Passing the stream past at least one source of light which produces radiation parallel to the thickness d, d being 10 μm to 1000 μm;and devices for executing the process.