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Analogues of lipid mediators derived from ω-3 PUFAs and methods of use
Analogues of lipid mediators derived from ω-3 PUFAs and methods of use
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机译:源自ω-3PUFA的脂质介体的类似物及其使用方法
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摘要
The present invention is directed to compounds that are analogues of lipid mediators derived from a fish oil-derived fatty acid, eicosapentaenoic acid [C20:5 ω-3; EPA], but with a longer tissue half-life and enhanced bioactivity. These analogues may be used to treat inflammatory, angioproliferative, cardiovascular, thrombophlebotic, vascular, ocular, dermatologic, neurodegenerative, pulmonary, endocrine, reproductive, rheumatologic and gastrointestinal diseases.
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