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Compounds useful as serotonin inhibitors and 5-HT1A agonists and antagonists

机译:可用作5-羟色胺抑制剂和5-HT 1A 激动剂和拮抗剂的化合物

摘要

3-Amino chroman and 2-amino tetralin derivatives and compositions containing such compounds are disclosed. Such compounds are useful for modulating activity of a 5-HT1A receptor (agonizing or antagonizing) in a patient. These compounds are further useful for inhibiting binding to a serotonin receptor. Methods of using the 3-amino chroman and 2-amino tetralin compounds and compositions containing such compounds in the treatment of serotonin disorders, such as depression and anxiety, are also disclosed.
机译:公开了3-氨基苯并二氢吡喃和2-氨基四氢萘衍生物及其组合物。此类化合物可用于调节患者体内5-HT 1A 受体的活性(激动或拮抗)。这些化合物还可用于抑制与5-羟色胺受体的结合。还公开了使用3-氨基苯并二氢吡喃和2-氨基四氢萘化合物以及包含此类化合物的组合物治疗5-羟色胺疾病例如抑郁症和焦虑症的方法。

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