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Growth and differentiation of adult muscle stem cells with activators or inhibitors of Wnt signaling
Growth and differentiation of adult muscle stem cells with activators or inhibitors of Wnt signaling
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机译:具有Wnt信号激活剂或抑制剂的成年肌肉干细胞的生长和分化
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摘要
Compositions and methods for modulating proliferation and/or lineage commitment of stem cells by modulating the Wnt signalling pathways. Modulators of the Wnt signalling pathways and screening methods to identify modulators are also provided. The methods of the invention may be conducted in vitro or in vivo to induce or inhibit stem cell proliferation and/or lineage commitment, and are particularly useful for in vivo stimulation of proliferation and/or lineage commitment of resident stem cells in a tissue.
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