Methods for immunoagglutination in polystyrene micro and nanospheres

摘要

METHODS FOR IMMUNOAGLUTINATION IN MICRO AND POLYSTYRENE NANOPHESES. The present invention relates to methods of using colored latex micro and nanospheres, activated with different chemical groups and sensitized with antigen (s) and / or antibody-carrying filamentous bacteriophages, which favor the formation of antigen-complexes. antibody, peptide-protein or peptide-substrate, enhancing optical detection during separation by chromatography or microagglutination under light microscopy and can be used for the detection of biomolecules or chemicals associated with infectious, parasitic, genetic and environmental contaminants, exemplified by by: tetanus, tuberculosis, leprosy, meningitis, dengue, AIDS, hepatitis, toxoplasmosis, leishmaniasis, malaria, various types of cancer, Alzheimer's disease, Parkinson's disease, cystic fibrosis, some hypercholesterolemia and anemia, phenylketonuria, multiple sclerosis, among others, fast, accurate, sensitive and reproducible small volumes of samples and reagents, with practicality and low costs.