genetically modified sequence of plasmodium vivax antigen dbp (am), recombinant dbp protein and genetically modified adenovirus expressing recombinant dbp antigen

摘要

GENETICALLY MODIFIED SEQUENCE OF PLASMODIUM VIVAX ANTIGEN DBP (AM), DBP RECOMBINANT PROTEIN AND GENETICALLY MODIFIED ADENOVIRUS EXPRESSING RECOMBINANT DBP ANTIGEN. The present invention relates to the construction of a modified gene sequence of Plasmodium vivax DBP (Duffy-Binding Protein) antigen obtained from a patient (AM), a recombinant protein encoded by said sequence and a genetically modified adenovirus expressing recombinant DBP antigen. . The invention is useful for mammalian immunization against malaria.