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K-RAS AND B-RAF MUTATIONS AND ANTI-EGFR ANTIBODY THERAPY.
K-RAS AND B-RAF MUTATIONS AND ANTI-EGFR ANTIBODY THERAPY.
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机译:K-RAS和B-RAF突变和抗EGFR抗体治疗。
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摘要
The present application relates to K-ras mutations, to polynucleotides encoding mutant K-ras polypeptides, and to methods of identifying K-ras mutations. The present application also relates to B-raf mutations, to polynucleotides encoding mutant B-raf polypeptides, to vectors containing those polynucleotides, and to methods of identifying B-raf mutations. The present application also relates to methods of diagnosing cancer; and methods and kits for predicting the usefulness of anti-EGFr specific binding agents in the treatment of tumors.
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