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Preparation of antigen-presenting human gamma delta T cells and use in immunotherapy
Preparation of antigen-presenting human gamma delta T cells and use in immunotherapy
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机译:抗原递呈人γδT细胞的制备及其在免疫治疗中的应用
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摘要
Provided is a method for the preparation of efficient antigen-presenting human gamma delta T cells comprising selecting gamma delta T cells out of human peripheral blood mononuclear cells, treating the selected cells with a stimulus for induction of antigen-presenting functions, and applying the antigen for uptake and presentation by these cells. Further provided are antigen presenting gamma delta T cell produced by the method, use of said T cells for the manufacture of a vaccine and related methods of identifying novel antigens and diagnosis patient immunocompetence.
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