Regulation of cytotrophoblast cell differentiation and cell migration

摘要

Disclosed is the use of one or more of IGF-II, a precursor of IGF-II, an isomer of IGF-II, and an analogue of IGF-II in the preparation of a medicament for administration to a female human to prevent and/or treat one or more of implantation failure, recurrent spontaneous miscarriage, pre-eclampsia, intrauterine growth restriction, and placental abruption.