首页> 外国专利> Salts maleate e - N - (4 - 3-chloro-4 - 2 piridinilmetoxi anilino - 7 - ethoxy - 3 - cyano - 4 - 6 - quinolinil} - 2 - (dimethylamino butenamide, Crystalline forms, processes for their preparation, and Methods for their use

Salts maleate e - N - (4 - 3-chloro-4 - 2 piridinilmetoxi anilino - 7 - ethoxy - 3 - cyano - 4 - 6 - quinolinil} - 2 - (dimethylamino butenamide, Crystalline forms, processes for their preparation, and Methods for their use

机译:马来酸盐[e]-N-(4-[3-氯-4-[2]吡咯烷二甲基苯胺基]-7-乙氧基-3-氰基-4-6-喹啉}}-2-[((二甲氨基丁烯酰胺,晶体形式,制备过程和使用方法

摘要

Forms of maleate Salt of (e) - N - 4 - 3 - Chloro - 4 - (2 - piridinilmetoxi anilino) - ethoxy - 3 - cyano - 4 - 6 - quinolinil - 4 - (dimethylamino) - 2 - /, Methods for preparing Crystalline forms of maleate Salt, Associated compounds. Pharmaceutical compositions containing salts of maleate.Maleate salts are useful in the treatment of cancer, particularly those affected by Family Kinases of the epidermal growth factor receptor.
机译:(e)-N-4-3-氯-4-(2-piridinilmetoxi anilino)-乙氧基-3-氰基-4-6-喹啉-4-(二甲氨基)-2- /的马来酸盐形式用于制备马来酸盐,相关化合物的结晶形式。含有马来酸盐的药物组合物。马来酸盐可用于治疗癌症,特别是受表皮生长因子受体的家族激酶影响的那些。

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