首页> 外国专利> Immunogenic formulation, because it comprises a recombinant attenuated strain of Mycobacterium, preferably recombinant Strain Bacillus of Calmette and Guerin (BCG), which expresses at least one Protein or immunogenic Fragment of respiratory virus SINC

Immunogenic formulation, because it comprises a recombinant attenuated strain of Mycobacterium, preferably recombinant Strain Bacillus of Calmette and Guerin (BCG), which expresses at least one Protein or immunogenic Fragment of respiratory virus SINC

机译:免疫原性制剂,因为它包含分枝杆菌的重组减毒株,最好是表达至少一种呼吸道病毒SINC的蛋白或免疫原性片段的重组卡介苗和芽孢杆菌芽孢杆菌(BCG)

摘要

Refers to an immunogenic formulation containing: (a) a recombinant Strain attenuated Mycobacterium Strain of the Bacillus of Calmette and Guerin (BCG) at a concentration of 104 - 109 bacteria, which expresses at least one Protein or immunogenic Fragment of respiratory syncytial virus (RSV), a A buffered saline solution.Where the genes that encode for Proteins VRS are inserted in the Genome of Mycobacterium and these Proteins belong to the subtypes VRS VRS VRS a or B, or both.This formulation can be used with other formulations and is immunogenic, formulated for Subcutaneous Administration, Percutaneous or subdermal in physiological Saline to be useful for treating infections caused by Respiratory syncytial virus (RSV)
机译:指包含以下成分的免疫原性制剂:(a)重组卡介苗和游击芽孢杆菌的减毒分枝杆菌菌株(BCG),其浓度为104-109个细菌,其表达至少一种呼吸道合胞病毒(RSV)的蛋白或免疫原性片段),一种A缓冲盐溶液,其中将编码VRS蛋白质的基因插入分枝杆菌的基因组中,并且这些蛋白质属于VRS VRS VRS a或B的亚型,或两者均属于亚型。具有免疫原性,配制用于生理盐水中的皮下给药,经皮或皮下,可用于治疗由呼吸道合胞病毒(RSV)引起的感染

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