首页> 外国专利> DERIVATIVES OF N-/PHENYL(ALKYLPIPERIDINE-2-YL)METHYL/ BENZAMIDE, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS

DERIVATIVES OF N-/PHENYL(ALKYLPIPERIDINE-2-YL)METHYL/ BENZAMIDE, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS

机译:N- /苯基(烷基哌啶-2-基)甲基/苯甲酰胺的衍生物,其制备方法及在治疗中的应用

摘要

The invention relates to compounds having general formula (I), wherein: R1 represents a hydrogen atom, an alkyl group, a cycloalkyl group, a cycloalkylalkyl group, a phenylalkyl group, an alkenyl group, or an alkynyl group; R2 represents an alkyl group, a cycloalkyl group, or a cycloalkylalkyl group; X represents a hydrogen atom or one or more halogen atoms and/or trifluoromethyl, alkyl or alkoxy groups; R3 represents a hydrogen atom, or one or more halogen atoms and/or trifluoromethyl, alkyl cycloalkyl, alkoxy, phenyl, cyano, acetyl, benzoyl, thioalkyl, alkylsulfonyl, carboxy or alkoxycarbonyl groups, or a group having formula NR4R5 or SO2NR4R5 or CONR4R5 in which R4 and R5 each represent a hydrogen atom or an alkyl or cycloalkyl group or NR4R5 represents a pyrrolidine, piperidine or morpholine ring. The invention also relates to the use of said compounds in therapeutics.
机译:本发明涉及具有通式(I)的化合物,其中:R 1代表氢原子,烷基,环烷基,环烷基烷基,苯基烷基,烯基或炔基; R 2表示烷基,环烷基或环烷基烷基。 X代表氢原子或一个或多个卤素原子和/或三氟甲基,烷基或烷氧基; R 3代表氢原子,或一个或多个卤素原子和/或三氟甲基,烷基环烷基,烷氧基,苯基,氰基,乙酰基,苯甲酰基,硫代烷基,烷基磺酰基,羧基或烷氧基羰基,或在式中具有式NR4R5或SO2NR4R5或CONR4R5的基团其中R4和R5分别代表氢原子或烷基或环烷基,或NR4R5代表吡咯烷,哌啶或吗啉环。本发明还涉及所述化合物在治疗中的用途。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号