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METHOD FOR EXPERIMENTAL MODELING OF EROSIVE-ULCERATING LESIONS OF GASTRIC AND DUODENAL MUCOSA IN RATS WITH AMMONIA HYDROXIDE

机译:氢氧化铵对大鼠胃黏膜和十二指肠黏膜侵蚀性溃疡的实验研究

摘要

A method for the experimental modeling of erosive-ulcerating lesions of the gastric and duodenal mucosa in the experimental animals, namely rats, comprises the use of ammonia hydroxide as the product of metabolism in HP infection. The prepared 1-2% solution of ammonia hydroxide is administered to the stomach of fasted rats through the probe under light ether narcosis in a volume of 1-2 mL. Then the animals are deprived of fodder and water for further one day.
机译:用于在实验动物即大鼠中对胃和十二指肠粘膜糜烂性溃疡病变进行实验建模的方法包括使用氢氧化氨作为HP感染中新陈代谢的产物。在轻醚麻醉下,通过探针将制备的1-2%氢氧化氨溶液通过探针施用于禁食大鼠的胃中,体积为1-2 mL。然后将动物剥夺饲料和水一天。

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