首页> 外国专利> SUPPORT FOR THE DETECTION OF GENES AND ITS USE FOR THE DETECTION OF THE EFFECTIVENESS OF THERAPY WITH INTERFERON.

SUPPORT FOR THE DETECTION OF GENES AND ITS USE FOR THE DETECTION OF THE EFFECTIVENESS OF THERAPY WITH INTERFERON.

机译:支持基因检测及其在干扰素治疗中的有效性检测。

摘要

A method for determining the validity of interferon treatment in an HCV infected individual, the method comprising determining the nucleotide identity of a single nucleotide polymorphism (SNP) in the promoter region of the MxA gene in a sample of the individual, corresponding position of the polymorphism with position 455 of SEQ ID No. 1, the presence of thymine being in said position indicative of the validity of the treatment and the presence of a nucleotide other than thymine in said position indicative of the invalidity of the treatment.
机译:一种确定在HCV感染个体中干扰素治疗有效性的方法,该方法包括确定个体样品中MxA基因启动子区域中单核苷酸多态性(SNP)的核苷酸同一性,多态性的相应位置在SEQ ID No.1的455位上,胸腺嘧啶在所述位置上指示治疗的有效性,而胸腺嘧啶以外的核苷酸在所述位置指示治疗的无效。

著录项

  • 公开/公告号ES2316420T3

    专利类型

  • 公开/公告日2009-04-16

    原文格式PDF

  • 申请/专利权人 KABUSHIKI KAISHA TOSHIBA;

    申请/专利号ES20010302705T

  • 申请日2001-03-22

  • 分类号C12Q1/68;G01N33/53;A01K67/027;A61K48;C07K14/47;C12M1;C12M1/34;C12N15/09;C12N15/63;C12Q1/70;C40B40/06;C40B40/10;C40B60/14;G01N37;

  • 国家 ES

  • 入库时间 2022-08-21 19:23:56

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