首页> 外国专利> DERIVATIVES OF AMINO-BENCIMIDAZOLES AS INHIBITORS OF THE REPLICATION OF THE SYNTHETIC RESPIRATORY VIRUS.

DERIVATIVES OF AMINO-BENCIMIDAZOLES AS INHIBITORS OF THE REPLICATION OF THE SYNTHETIC RESPIRATORY VIRUS.

机译:作为合成呼吸道病毒复制抑制剂的氨基苯甲酰唑衍生物。

摘要

A compound of formula (I): ** (See formula) ** an N-oxide, addition salt, quaternary amine, metal complex or stereochemically isomeric form thereof, wherein Q is C 1-6 alkyl substituted with 1 or 2 hydroxy substituents; G is methylene; R 1 is pyridyl substituted with 1 or 2 substituents independently selected from the group consisting of hydroxy and C 1-6 alkyl; one of R 2a and R 3a is C 1-6 alkyl and the other of R 2a and R 3a is hydrogen; in the case where R 2a is different from hydrogen, then R 2b is hydrogen or C 1-6 alkyl, and R 3b is hydrogen; in the case where R 3a is different from hydrogen, then R 3b is hydrogen or C1-6 alkyl, and R 2b is hydrogen; or R 2a, R 2b, R 3a and R 3b are all hydrogen; R 5 is hydrogen or C 1-6 alkyl.
机译:式(I)的化合物:**(参见式)** N-氧化物,加成盐,季胺,金属络合物或立体化学异构形式,其中Q为被1个或2个羟基取代基取代的C 1-6烷基; G为亚甲基; R 1是被1或2个独立地选自羟基和C 1-6烷基的取代基取代的吡啶基; R 2a和R 3a中的一个为C 1-6烷基,R 2a和R 3a中的另一个为氢。在R 2a与氢不同的情况下,R 2b为氢或C 1-6烷基,R 3b为氢。在R 3a与氢不同的情况下,R 3b为氢或C 1-6烷基,R 2b为氢。 R 2a,R 2b,R 3a和R 3b均为氢;或R 5是氢或C 1-6烷基。

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