EYA2S AS MODIFIERS OF THE PTEN/AKT PATHWAY AND METHODS OF USE

摘要

Human EYA2 genes are identified as modulators of the PTEN/AKT pathway, and thus are therapeutic targets for disorders associated with defective PTEN/AKT function. Methods for identifying modulators of PTEN/AKT, comprising screening for agents that modulate the activity of EYA2 are provided.