CRYSTALLINE FORMS OF EFAVIRENZ

摘要

The present invention provides a novel solid form of Efavirenz, crystalline form of Efavirenz with sodium deoxycholate, designated Efavirenz : sodium deoxycholate,, methods for the preparation of Efavirenz : sodium deoxycholate, and the use of Efavirenz: sodium deoxycholate, in pharmaceutical applications, in particular in anti- HIV medicaments. The crystalline form of Efavirenz : sodium deoxycholate, can be used in combination with other anti-HIV medicaments such as Tenofovir DF and Emtricitabine.