MURINE ENDOMETRIOSIS MODELLED BY K-RAS ACTIVATION OF MENSTRUATING ENDOMETRIUM

摘要

This invention relates to the production of rodent endometriosis models by implanting into wild type recipient rodents menstruating endometrium from donor rodents in which an oncogene, such as K-ras, has been activated. Rodent endometriosis models and methods of production and use of such models in screening for therapeutics are provided.