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NOVEL APOPTOSIS INDUCING FACTOR AND METHOD OF INDUCING APOPTOSIS USING THE SAME
NOVEL APOPTOSIS INDUCING FACTOR AND METHOD OF INDUCING APOPTOSIS USING THE SAME
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机译:新型凋亡诱导因子和使用该因子诱导凋亡的方法
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摘要
The purpose of the present invention is to provide a system in which an apoptosis-inducing factor is expressed in an expression promoter-dependent manner, which is not a system wherein a toxin is introduced externally, and a novel protein that can enhance an apoptosis signal used in the system.;The present invention relates to An apoptosis-inducing factor comprising a fusion protein of a polypeptide comprising FADD or a constituting domain thereof and a protein with a self-assembling activity, an expression vector comprising DNA encoding the apoptosis-inducing factor, a transgenic animal having the expression vector introduced therein, an animal wherein apoptosis is induced in a specific cell or tissue and/or at a specific time and a method for producing the animal.
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