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Collagen fibrils carrying bioactive heterologous domains and their use in e.g. wound healing
Collagen fibrils carrying bioactive heterologous domains and their use in e.g. wound healing
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机译:带有生物活性异源结构域的胶原原纤维及其在例如胶原蛋白中的用途。伤口愈合
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摘要
A modified pro-α chain comprising a triple helix forming domain linked to at least an N-terminal domain, the N-terminal domain containing a polypeptide from at least part of a laminin glycoprotein or secretory leukocyte protease inhibitor. The pro-α chain may form part of a procollagen molecule that has the N-terminal domain retained. The procollagen molecules may be incorporated into collagen polymers, matrices and gels and be used for such applications as wound healing.
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