首页> 外国专利> SUGAR CHAIN ARRAY SUBSTRATE AND METHOD FOR DETECTION OF SUGAR CHAIN-BINDING MOLECULE USING THE SAME

SUGAR CHAIN ARRAY SUBSTRATE AND METHOD FOR DETECTION OF SUGAR CHAIN-BINDING MOLECULE USING THE SAME

机译:糖链阵列基质和使用该糖链结合分子的糖链分子检测方法

摘要

A sugar chain array substrate capable of presenting a sugar chain molecule in a polyvalent state by immobilizing a sugar chain-carrier complex in which a plurality of the same type of sugar chain molecules are bound to one carrier molecule on a substrate at a predetermined position is provided. Further, a sugar chain array substrate in which a purified or unpurified complex sugar is immobilized on the sugar chain array substrate at another predetermined position is provided. Further, the invention provides a method and a kit for detection or analysis of a sugar-binding molecule in a test sample, analysis of a sugar-binding activity of a test sugar-binding molecule, detection or analysis of a sugar chain in a complex sugar, search for a sugar-binding molecule having an unknown sugar-binding activity using the sugar chain array substrate.
机译:通过固定其中多个相同类型的糖链分子结合到基板上的预定位置上的一个载体分子的糖链-载体复合物,能够以多价状态呈现糖链分子的糖链阵列基质是提供。此外,提供了一种糖链阵列基板,其中在另一预定位置上将纯化的或未纯化的复合糖固定在糖链阵列基板上。此外,本发明提供了用于检测或分析测试样品中的糖结合分子,分析测试的糖结合分子的糖结合活性,检测或分析复合物中的糖链的方法和试剂盒。糖,使用糖链阵列底物寻找具有未知糖结合活性的糖结合分子。

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