A preventive and/or a remedy for lower urinary tract diseases such as inflammation in the lower urinary tract, cystitis (interstitial cystitis, etc.) and urethritis; (2) an agent for improving bladder compliance and/or bladder capacity; and (3) an agent for protecting bladder mucosa and/or bladder epithelial cells and/or promoting the regeneration thereof; each containing an EP 4 agonist. An EP 4 agonist is useful in ameliorating symptoms of lower urinary tract diseases such as (1) frequent urination, (2) urgency of urination, (3) pain in the reproductive organs and/or lower urinary tract (for example, bladder pain, urinary tract pain, vulvar pain, vaginal pain, scrotal pain, perineal pain, pelvic pain, etc.) and/or (4) discomfort in the reproductive organs and/or lower urinary tract. Among all, a selective EP 4 agonist is useful as a preventive and/or remedy for lower urinary tract diseases having no side effect.
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机译：对下尿路疾病的预防和/或治疗，例如下尿路炎症，膀胱炎（间质性膀胱炎等）和尿道炎; （2）用于改善膀胱顺应性和/或膀胱容量的试剂; （3）保护膀胱粘膜和/或膀胱上皮细胞和/或促进其再生的药剂。每个都包含EP 4激动剂。 EP 4激动剂可用于缓解下尿路疾病的症状，例如（1）尿频，（2）尿急，（3）生殖器官和/或下尿路疼痛（例如，膀胱疼痛，尿路痛，外阴痛，阴道痛，阴囊痛，会阴痛，骨盆痛等）和/或（4）生殖器官和/或下尿路不适。其中，选择性EP 4激动剂可用作无副作用的下尿路疾病的预防和/或治疗。
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