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LIGAND FOR VESICULAR ACETYLCHOLINE TRANSPORTER

机译:膀胱乙酰胆碱转运蛋白配体

摘要

Wherein, compounds shown in the present invention is intended to provide are by formula (I): (R1 and R2, which has the same meaning, to be defined as in the description) it is used as the mapping of reagent VAChT (labelled atom etc.), it can be used for positron emission tomography (PET), its salt and the method for manufacturing the compound. It would also be desirable to provide a kind of diagnosticum, comprising the compound for diagnosing cholinergic nerve degenerative disease (such as Alzheimer disease, learning memory disorder, learning disability, schizophrenia, cognitive dysfunction, hyperactivity, anxiety neurosis, depression, analgesic or Parkinson's disease) etc..
机译:其中,本发明所示的化合物旨在由式(I)提供:(R1和R2,其含义与说明书中所定义的相同)被用作试剂VAChT(标记的原子)的图谱。等),可用于正电子发射断层扫描(PET),其盐和化合物的制备方法。还需要提供一种诊断物,其包括用于诊断胆碱能神经退行性疾病(例如阿尔茨海默氏病,学习记忆障碍,学习障碍,精神分裂症,认知功能障碍,活动过度,焦虑神经症,抑郁症,镇痛或帕金森氏病的化合物) )等。

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