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The ligand for the vesicular acetylcholine transporter

机译:水泡乙酰胆碱转运蛋白的配体

摘要

It is intended to provide a novel compound represented by the formula (I): (wherein R1 and R2 have the same meaning as defined in the specification) useful as a reagent for mapping of VAChT (radiotracer) or the like, which can be used for positron emission tomography (PET), a salt thereof and a method for producing the compound. It is also intended to provide a diagnostic agent containing the compound for diagnosing a cholinergic neurodegenerative disease (such as Alzheimer’s disease, dysmnesia, learning disability, schizophrenia, cognitive dysfunction, hyperactivity disorder, anxiety neurosis, depression, analgesia, or Parkinson’s disease) or the like.
机译:旨在提供由式(I)表示的新型化合物:(其中R1和R2具有与说明书中定义的相同的含义)可用作用于绘制VAChT(放射性示踪剂)等的试剂。用于正电子发射断层扫描(PET)的盐,其盐以及制备该化合物的方法。还旨在提供含有用于诊断胆碱能神经退行性疾病(例如阿尔茨海默氏病,记忆障碍,学习障碍,精神分裂症,认知功能障碍,多动症,焦虑神经症,抑郁,镇痛或帕金森氏病)的化合物的诊断剂喜欢。

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