METHOD FOR PREVENTING AND/OR TREATING A DISEASE, CONDITION OR STATE ASSOCIATED WITH REDUCED DOPAMINERGIC NEURON FUNCTION

摘要

The present invention relates to a method of preventing and/or treating a disease, condition or state associated with reduced dopaminergic neuron function in a subject. The method includes the step of administering to the subject an effective amount of a substance P receptor antagonist. The present invention also relates to the administration of a substance P receptor antagonist to a subject in methods for inhibiting progression of a disease, condition or state associated with reduced dopaminergic neuron function in the subject, or for alleviating one or more complications in the subject which are associated with administration of a dopaminergic agent. Pharmaceutical compositions and combination products which include a substance P receptor antagonist are also described.