首页> 外国专利> A MOLECULE FOR PROVIDING A STANDARD FOR THE QUANTITATIVE ANALYSIS OF THE METHYLATION STATUS OF A NUCLEIC ACID

A MOLECULE FOR PROVIDING A STANDARD FOR THE QUANTITATIVE ANALYSIS OF THE METHYLATION STATUS OF A NUCLEIC ACID

机译:一种提供核酸甲基化状态定量分析标准的分子

摘要

The invention refers to a nucleic acid for providing a standard in the quantitative bisulfite based analysis of the methylation status of a DNA molecule with a given sequence, wherein the given sequence comprises at least one CpG position that is to be analyzed for its methylation status. This nucleic acid comprises: a first and a second sequence portion, both of which comprise at least part of the given sequence with at least one CpG position, wherein in the first sequence portion, all of the CpG positions represent the methylated status, and in the second sequence portion, all of the CpG positions represent the unmethylated status.
机译:本发明涉及用于在基于亚硫酸氢盐的定量分析中对具有给定序列的DNA分子的甲基化状态提供标准的核酸,其中给定序列包含至少一个要分析其甲基化状态的CpG位置。该核酸包含:第一和第二序列部分,两者均包含具有至少一个CpG位置的给定序列的至少一部分,其中在第一序列部分中,所有CpG位置均代表甲基化状态,并且在在第二序列部分,所有的CpG位置代表未甲基化状态。

著录项

  • 公开/公告号EP2087137A1

    专利类型

  • 公开/公告日2009-08-12

    原文格式PDF

  • 申请/专利权人 EPIGENOMICS AG;

    申请/专利号EP20070825755

  • 发明设计人 SCHATZ PHILIPP;

    申请日2007-10-15

  • 分类号C12Q1/68;

  • 国家 EP

  • 入库时间 2022-08-21 19:15:08

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