CELL PERMEABLE P66SHC FUSION PROTEIN HAVING ANTI-CANCER ACTIVITY

摘要

A cell penetrating fusion protein Tat-p66shc, a gene coding the fusion protein, an expression vector containing the gene, and the transformed E. coli are provided to obtain the fusion protein having the anticancer activity. A cell penetrating fusion protein Tat-p66shc is the fusion protein that the human p66shc protein is fused with the protein transduction domain of the Tat protein, and is represented by the sequence number 1. Preferably the gene coding the fusion protein Tat-p66shc is represented by the sequence number 2. The E. coli transformed by the expression vector containing the gent is deposited (deposition number KCTC 11138BP).