Topical Formulation Composed of Cell Permeable Vascular Endothelial Growth Factor LMWP-VEGF fusion protein with Skin Physiological Activity

摘要

The present invention relates to a composition for external application for skin containing a cell-permeable vascular endothelial cell growth factor fusion protein, and a cell external composition for cell-permeable cell permeation-containing vascular endothelial cell growth factor fusion protein is non-toxic to skin cells. Since the bio-active material contained in the protein has excellent cell permeability, it can be particularly effectively used for skin improvement (recovery), anti-aging or wound healing. In addition, the cell-permeable vascular endothelial cell growth factor fusion protein according to the present invention further comprises 1,2-hexanediol (Hexanediol), thereby exhibiting a remarkable synergistic effect in promoting collagen production, further anti-aging or wound healing. Can be used effectively.