首页> 外国专利> PHARMACEUTICAL COMPOSITION COMPRISING SUBSTITUTED BENZENE ANALOG COMPOUND WITH NEUROPROTECTIVE ACTIVITIES FOR THE TREATMENT OF NEUROLOGICAL BRAIN DISEASE COMPRISING PARKINSON'S DISEASE AND METHOD FOR TREATING BRAIN DISORDER USING THE COMPOUNMD

PHARMACEUTICAL COMPOSITION COMPRISING SUBSTITUTED BENZENE ANALOG COMPOUND WITH NEUROPROTECTIVE ACTIVITIES FOR THE TREATMENT OF NEUROLOGICAL BRAIN DISEASE COMPRISING PARKINSON'S DISEASE AND METHOD FOR TREATING BRAIN DISORDER USING THE COMPOUNMD

机译:包含取代类似物和神经保护活性的苯酚类似物的药物组合物,用于治疗包括帕金森氏病在内的神经性疾病,以及使用该化合物治疗脑部疾病的方法

摘要

The present invention is a substituted benzene derivative or a Parkinson's disease, comprising an effective amount of an acceptable salt of a pharmaceutically, epilepsy, depression, pain, anxiety and brain disease therapeutic pharmaceutical composition containing a degenerative brain disorders and it relates to a brain disease treatment methods, including Parkinson's disease, epilepsy, depression, pain, anxiety, and neurodegenerative diseases of a mammal, characterized by administering an effective amount the compound in mammals, ; Formula (I) benzene derivatives and useful salts thereof pharmaceutically MAO-B activity Na + channel, the dopamine transporter, norepinephrine transporter, and by engaging the action of a serotonin receptor bottle's Parkinson's treatment, including the inhibitory effect of It has a potency and brain cell protection effect is effective in epilepsy, depression, anxiety and pain therapy. ; Formula (I) ; Benzene derivatives, Parkinson's disease, epilepsy, depression, pain, anxiety, neurodegenerative diseases, dopamine
机译:本发明是取代苯衍生物或帕金森氏病,其包含有效量的含有变性脑疾病的药学,癫痫,抑郁,疼痛,焦虑和脑病治疗药物组合物的可接受的盐,并且它涉及脑病治疗方法,包括帕金森氏病,癫痫,抑郁,疼痛,焦虑症和哺乳动物的神经退行性疾病,其特征在于在哺乳动物中施用有效量的化合物,式(I)苯衍生物及其有用的盐具有药物的MAO-B活性Na + 通道,多巴胺转运蛋白,去甲肾上腺素转运蛋白,并通过参与5-羟色胺受体瓶的帕金森氏病的治疗,包括抑制作用它具有强大的功效,对脑细胞的保护作用在癫痫,抑郁症,焦虑症和疼痛疗法中有效。 ;式(I);苯衍生物,帕金森氏病,癫痫,抑郁,疼痛,焦虑,神经退行性疾病,多巴胺

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