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METHOD FOR SCREENING INHIBITOR OF CELL CYCLE REGULATOR USING CAENORHABDITIS ELEGANS
METHOD FOR SCREENING INHIBITOR OF CELL CYCLE REGULATOR USING CAENORHABDITIS ELEGANS
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机译:利用盲肠念珠菌筛选细胞周期调节因子抑制剂的方法
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摘要
A method for screening a cell cycle control factor inhibitor is provided to screen easily drug of bulk in a fast date using Caenorhabditis elegans easy to be observed because a size of intestines nucleus is greater than the nucleus of the other cells. A method for screening a cell cycle control factor inhibitor includes steps of: processing testing material when cultivating Caenorhabditis elegans mutant overexpressing CDC-25 which is a cell cycle control factor; and confirming intestines nucleus number of the Caenorhabditis elegans mutant and confirming CDC-25 deterrent effect. The Caenorhabditis elegans mutant over-expressing the CDC-25 is the Caenorhabditis elegans rr31 mutant.
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