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A vector for cell surface expression of pig IgG Fc domian, a host cell transformed with the vector, a vaccine against viruses related to pig diseases and a manufacturing method of the same using the host cell
A vector for cell surface expression of pig IgG Fc domian, a host cell transformed with the vector, a vaccine against viruses related to pig diseases and a manufacturing method of the same using the host cell
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机译:用于猪IgG Fc domian的细胞表面表达的载体,用该载体转化的宿主细胞,与猪疾病有关的病毒的疫苗及其使用该宿主细胞的制造方法
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摘要
A vector for cell surface expression of Fc(Crystallized Fragment) domain of pig immunoglobulin G is provided to facilitate a manufacturing process of vaccines with excellent immunogenicity against various viruses, which cause pig's diseases. A vector for cell surface expression of Fc(Crystallized Fragment) domain of pig immunoglobulin G comprises a gene for coding a transmembrane domain of a pig transferrin receptor and a gene for coding a Fc domain of pig immunoglobulin G. The gene for coding a transmembrane domain indicates a sequence number 3 or the sequence number 16. The gene for coding the Fc domain is a gene for coding CH2 and CH3.
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