APPLICATION 4- (3,4-Dichlorophenyl) -1,2,3,4-TETRAHYDRONAFTALIN-1-ILAMINE FOR THE TREATMENT OF CANCER

摘要

1. The use of 4- (3,4-dichlorophenyl) -1,2,3,4-tetrahydronaphthalen-1-ylamine or any combination of its enantiomers or one of its enantiomers as active ingredients, alone or in combination with at least one alkaloid for the manufacture of a pharmaceutical composition for the treatment of cancer and for the treatment and prevention of metastases. ! 2. The use according to claim 1, characterized in that the alkaloid is a vinca alkaloid. ! 3. The use according to claim 2, characterized in that the vinca alkaloid is selected from the group consisting of: vinblastine, vincristine, vindesine, vinorelbine or mixtures thereof, preferably vincristine and / or vinblastine. ! 4. The use according to claim 1, characterized in that said cancer or said metastases are derived from cancer selected from the group consisting of prostate cancer, osteosarcoma, lung cancer, non-small cell lung cancer, breast cancer, endometrial cancer or colon cancer , chronic or acute leukemia, solid tumors in children, lymphocytic lymphomas, pancreatic cancer, skin cancer, skin or intraocular melanoma, head and neck cancer, uterine cancer, ovarian cancer, gynecological tumors, Hodgkin's disease, bone cancer, cancer rectal cancer, anal cancer, gastric cancer, esophageal cancer, small intestine cancer, endocrine cancer, soft tissue sarcoma, urethral cancer, penile cancer, bladder cancer, kidney cancer, ureter cancer, malignant tumors in children and central nervous system tumors system. ! 5. The use according to claim 4, characterized in that said cancer is breast cancer or said metastases are derived from cancer